To learn precisely how that fungus interacts with bacteria to trigger CD, Ghannoum has received a five-year, $3 million grant from the National Institutes of Health. His investigation will involve innovative molecular and cellular technologies, to delete specific genes in the fungus and note the effects on the inflammation that is a marker for CD using powerful microscopic analysis.
Increases in various fungal infections due to Candida, Aspergillus, Blastomyces, Histoplasma spp., and Dermatophytes have attracted interest in the biochemistry of the fungal pathogens responsible. This book discusses the importance of lipids in pathogenic fungi and how they are involved in infections that pose serious health problems.
This new edition of Antifungal Therapy aims at providing concise, practical, need-to-know information for busy physicians dealing with fungal infections, such as infectious disease physicians, transplant surgeons, dermatologists, and intensivists, as well as basic scientists and pharmaceutical company researchers interested in the state of antifungal therapy.
In Vitro and In Vivo Activity of a Novel Catheter Lock Solution against Bacterial and Fungal Biofilms
Central-line-associated bloodstream infections are increasingly recognized to be associated with intraluminal microbial biofilms, and effective measures for the prevention and treatment of bloodstream infections remain lacking.
Development of a 96-well Catheter-based Microdilution Method to Test Antifungal Susceptibility of Candida Biofilms
Candida biofilms, which are often associated with device-related infections, including catheter-related bloodstream infections, are resistant to commonly used antifungal agents.
Infections due to Candida parapsilosis have been associated with the ability of this fungus to form biofilms on indwelling medical devices.
Parenteral Lipid Emulsion Induces Germination of Candida Albicans and Increases Biofilm Formation on Medical Catheter Surfaces
The administration of parenteral nutrition, including lipid emulsion (LE), to patients via medical catheters is an unexplained risk factor for the development of candidemia.
Candida auris is an emerging multidrug-resistant yeast that has been responsible for invasive infections associated with high morbidity and mortality.