In Vitro and In Vivo Activity of a Novel Catheter Lock Solution against Bacterial and Fungal Biofilms
Central-line-associated bloodstream infections are increasingly recognized to be associated with intraluminal microbial biofilms, and effective measures for the prevention and treatment of bloodstream infections remain lacking.
Development of a 96-well Catheter-based Microdilution Method to Test Antifungal Susceptibility of Candida Biofilms
Candida biofilms, which are often associated with device-related infections, including catheter-related bloodstream infections, are resistant to commonly used antifungal agents.
Infections due to Candida parapsilosis have been associated with the ability of this fungus to form biofilms on indwelling medical devices.
Parenteral Lipid Emulsion Induces Germination of Candida Albicans and Increases Biofilm Formation on Medical Catheter Surfaces
The administration of parenteral nutrition, including lipid emulsion (LE), to patients via medical catheters is an unexplained risk factor for the development of candidemia.