Microbiome (fungal and bacterial) profiling compares the microbiota in various healthy and diseased conditions, and it provides insight into its polymicrobial interactions as a prelude to designing interventional approaches.
This service includes testing of both preclinical and clinical applications involving therapeutic prevention and treatment, as well as nutritional supplements (e.g., probiotics, prebiotics, micro-nutrients).
By utilizing microbiome profiling, NTS can reliably assess how the microbiome varies across different treatment groups in clinical trials and identify statistically significant associations between clinical indications and specific microbiome compositions. NTS has customized its pipeline to investigate how medical treatments, probiotics, prebiotics, and other interventions (e.g., dietary) change the abundance and diversity of different microbial taxons.
NTS can reliably assess how the microbiome varies across different treatment groups in clinical trials and identify statistically significant associations between clinical indications and specific microbiome compositions.
Characterization of the Oral Fungal Microbiome (Mycobiome) in Healthy Individuals
The oral microbiome-organisms residing in the oral cavity and their collective genome-are critical components of health and disease. The fungal
Characterization of Bacterial Communities in Venous Insufficiency Wounds by Use of Conventional Culture and Molecular Diagnostic Methods
To better understand bacterial communities in chronic wounds, we analyzed debridement samples from lower-extremity venous insufficiency ulcers using the following:
Oral Mycobiome Analysis of Hiv-infected Patients: Identification of Pichia as an Antagonist of Opportunistic Fungi
Mukherjee PK, Chandra J, Retuerto M, Sikaroodi M, Brown RE, Jurevic R, Salata RA, Lederman MM, Gillevet PM, Ghannoum MA.
Quorum-sensing Dysbiotic Shifts in the Hiv-infected Oral Metabiome
We implemented a Systems Biology approach using Correlation Difference Probability Network (CDPN) analysis to provide insights into the statistically significant
Bacteriome and Mycobiome Interactions Underscore Microbial Dysbiosis in Familial Crohn’s Disease
In the current study, we used Ion Torrent sequencing to characterize the gut bacterial microbiota (bacteriome) and fungal community